Pdf metal complexes of dithiocarbamate derivatives and its. Molecules free fulltext chemistry and some biological. The detailed study 1518 of various dithiocarbamates and their derivatives through infrared spectra confirms the contribution of various forms equally to the structure. Download hires image download to mspowerpoint cite this. Synthesis, characterization and electrochemical studies of. Synthesis and characterization of copperii dithiocarbamate complexes involving pyrrole and ferrocenyl moieties and their utility for sensing anions and preparation of copper sulfide and copperiron sulfide nanoparticles. Synthesis, structural and antibacterial study of some metal ion.
Us9492465b2 goldi complexes with tbutyl phosphine and. Pdf synthesis and characterization of homoleptic group. Synthesis, characterization and antifungal studies by botha nandipha loveness 200904696 b. The synthesized goldiii dithiocarbamate complexes were tested for their in vitro cytotoxic activity towards an array of human tumor cell lines and were noted to be 1 to 4fold more cytotoxic than cisplatin 12. Pdf synthesis and characterization of homoleptic group 10. Au surfaces are functionalized by stable dithiocarbamate ligands when exposed to carbon disulfide and secondary amines. Analysis of dithiocarbamate fungicides in vegetable matrices. Dithiocarbamatefunctionalized dendrimers as ligands for. Synthesis and characterization of copperii dithiocarbamate. Honours chemistry ufh being a dissertation submitted to the faculty of science and agriculture in fulfilment of the requirements for the award of the degree of. M ni, cu, pd, zn, n 10, 18 were reported by hoshinomiyajima, 790 who found that derivatives bound to ni, cu, and pd were mesomorphic, showing both nematic and smc mesophases at elevated temperatures, i. Synthesis, characterization and electrochemical studies of coii, iii dithiocarbamate complexes article pdf available in journal of coordination chemistry 725.
Iii dithiocarbamate complexes is on the rise, and this has been. Chlorodiphenyltiniv dithiocarbamate complexes as chemodosimeters and host for anions and neutral compounds in solution. Selenidomolybdenumv dithiocarbamate complexes springerlink. Apr 20, 2018 synthesis and characterization of copperii dithiocarbamate complexes involving pyrrole and ferrocenyl moieties and their utility for sensing anions and preparation of copper sulfide and copperiron sulfide nanoparticles. Density functional theory study of goldiiidithiocarbamate. Dithiocarbamate dtc fungicides are a group of organosulfur compounds represented by a general structure r1r2 nc ssx, where r can be substituted by an alkyl, alkylene, aryl or similar other group, and x is usually a metal ion, widely used in agriculture and frequently detected as pesticide residues in plant products in the world. Three dithiocarbamate complexes with europium, eus2cnrr3l, where l 1,10phenanthroline, and r methyl, r ethyl 1, r r npropyl 2, and r r ibutyl 3, as well as the lanthanide complexes, lns2cnr23 l, where r ethyl, l.
A new complex of znii that contain amino acid valine and dithiocarbamate. The molecular structures of the dithiophosphate complex moh5c 5 me 5cl 3 h 2s 2 poet 2 and the peroxo derivative moh5c 5 h 5. Dithiocarbamate article about dithiocarbamate by the free. Coiii n,ndiarylformamidine dithiocarbamate complexes. Synthesis, structural characterization, and antibacterial activity of novel erbiumiii complex containing antimony. A dithiocarbamate is a functional group in organic chemistry. A standard dimeric zinc dithiocarbamate structural motive, a rare cadmium dithiocarbamate coordination polymer, and a hydrated sodium. These goldi dithiocarbamate complexes show in vitro cytotoxic activities against a549 human lung carcinoma, hela human cervical cancer and mcf7 human breast cancer cell lines. Cyclopentadienyl dithiocarbamate and dithiophosphate. A range of metal dithiocarbamate complexes were synthesised and chapter 2 focusses on the synthesis of iron dithiocarbamates.
Synthesis and characterization of light lanthanide complexes. The reaction is a highly atomeconomic process for production of s alkyl thiocarbamates. Nickelii dithiocarbamate complexes containing the pyrrole. This is due to their ability to stabilize specific stereochemistry in. All the complexes have been characterized using elemental analysis, infrared and nmr 1 h and c spectroscopies and x. Synthesis and structural characterization of bismuthiii. These complexes also serve as useful precursors for different metal sulfide nanoparticles. Antioxidant activities of the dithiocarbamate salts and their coiii complexes were also investigated using dpph assay and the complexes were found to be more efficient.
Monomeric ruthenium dithiocarbamate complexes were also prepared as model compounds and their spectroscopic data compared with those of the metallodendrimers. Pdf chemistry and some biological potential of bismuth and. A continuous mass loss was observed in both ligand complexes of mercury and only 10% initial mass remained at 650c, owing to the volatile nature of mercury dithiocarbamates. Syntheses, characterization, and antimicrobial properties of nickelii dithiocarbamate complexes containing nis4 and nis2pn moieties. Thermal characterization studies on zinc, cadmium and mercury. Thermal characterization, zinc, cadmium and mercury dithiocarbamate complexes.
Synthesis and characterization of homoleptic group 10 dithiocarbamate complexes and heteroleptic niii complexes, and the use of the homoleptic niii for the preparation. The significant among several canonical forms for the dithicarbamates in. The complexes adopt cisoctahedral geometry with folded macrocyclic ligand and with the dithiocarbamate bound as a bidentate. Synthesis, spectra, crystal structures and anticancer. For their metabolite ethylenethiourea etu, an adi of 0 0.
It is the analog of a carbamate in which both oxygen atoms are replaced by sulfur atoms when only 1 oxygen is replaced the result is thiocarbamate a common example is sodium diethyldithiocarbamate. A large number of analogs of cisplatin have been tested, and it has been reported that many active complexes could react with cell dna and inhibit its synthesis 11 14. Nickelii dithiocarbamate complexes containing the pyrrole moiety for sensing anions and synthesis of nickel sulfide and nickel oxide nanoparticles e. Monomeric ruthenium dithiocarbamate complexes were also prepared as model compounds and their spectroscopic data compared with those of the. Synthesis and characterization of homoleptic group 10 dithiocarbamate complexes and heteroleptic niii complexes, and the use of the homoleptic niii for the preparation of nickel sulphide nanoparticles.
The alkyl r groups on the n atoms of dithiocarbamates could be varied with different organic groups such as alkyl and aryl derivatives. Progresses made in previous researches on syntheses of dithiocarbamates led to increase in further researches. Metal dithiocarbamate complexes possess many interesting and useful properties which has made them ubiquitous in the literature. Induced properties of heteroleptic copperi xanthatedithiocarbamate pph 3 complexes gunjan rajput department of chemistry, faculty of science, banaras hindu university, varanasi 221005, india, fax. Iron dithiocarbamate complexes may easily bind free no radicals to form a stable mononitrosyl iron complex. Us9492465b2 us15042,852 us201615042852a us9492465b2 us 9492465 b2 us9492465 b2 us 9492465b2 us 201615042852 a us201615042852 a us 201615042852a us 9492465 b2 us9492465 b2 us 9492465b2 authority us united states prior art keywords complexes au gold complex bu prior art date 20140319 legal status the legal status is an assumption and is not a legal conclusion. Cdpadtc 2 complexes and the final residue was found to be cds. Built on an ethos of openness, we are passionate about working with the global academic community to promote open scholarly research to the world. Pdf chemistry 211 synthesis, characterization and biological. May 03, 2005 au surfaces are functionalized by stable dithiocarbamate ligands when exposed to carbon disulfide and secondary amines.
The significant among several canonical forms for the dithicarbamates in their metal complexes, ms 2cnr 2n are as follows. Thermal characterization studies on zinc, cadmium and. Spectral studies show that the dithiocarbamate group. Both ironii and ironiii complexes were synthesised, the latter being a facile, open bench reaction producing a range of fes2cnrr3 complexes. No dithiocarbamatecomplexes trade name applications 1. Request pdf main group dithiocarbamate complexes dithiocarbamates, r2ncss. Interest in the synthesis of biiii and sbiii dithiocarbamate complexes is on the rise, and this has been attributed to their wide structural diversity and their interesting application as biological agents and in solid statematerials chemistry. These complexes are active against several cancer cells, with the most active compound able to act against ten cancer cells in vitro and with gi50 as low as 0.
A series of bimetallic dppfmii dppf 1,1bis diphenyphosphino ferrocene. Two new zinc and dithiocarbamate integrated metal complexes such as. Dithiocarbamates and their derivatives are widely used in the vulcanization of rubber. Mulkey, director signed office of pesticide programs 7501c to. Synthesis, characterisation and biological aspects of. Department of chemistry, faculty of science, banaras hindu university, varanasi 221005, india, fax. M pt and pd dithiocarbamate complexes is synthesized and characterized by spectroscopic methods and singlecrystal xray diffraction. On the synthesis, properties, and applications of metal. Synthesis and characterization of light lanthanide.
Us20150266909a1 goldi complexes with tbutyl phosphine. Dithiocarbamates dtcs are versatile chelating ligands with. The novel compounds were characterized using nmr spectroscopy 1h and c and mass spectrometry. Cid 3001860 dithiocarbamic acid expand this section. Effect of metal complexation on the degradation of dithiocarbamate fungicides. Dithiocarbamate ligands have shown very good binding ability by forming complexes with most transition and main group metals 1,2.
Analysis of dithiocarbamate fungicides in vegetable. Effect of metal complexation on the degradation of. Induced properties of heteroleptic copperi xanthatedithiocarbamate pph 3 complexes gunjan rajput. In vitro antibacterial and anticancer activity of znii iopscience. We have synthesized a series of lanthanide dithiocarbamate precursors for the synthesis of lanthanide sulfide materials and nanoparticles. Chemistry and some biological potential of bismuth and antimony dithiocarbamate complexes. Furthermore, transition metal dithiocarbamate complexes, prepared from a diverse range of new ligands, have been the focus of. Jul 17, 2019 all the complexes have been characterized using elemental analysis, infrared and nmr 1 h and c spectroscopies and x. Density functional theory study of goldiii dithiocarbamate complexes with characteristic anticancer potentials. Dithiocarbamate assembly on gold journal of the american. Phosphinogoldi complexes, featuring heterocycle dithiocarbamate ligands, have been synthesized and characterized. The disubstituted dithiocarbamates of cuii are stable, water insoluble compounds and under acidic conditions do. Both complexes 1 and 2 are isostructural having linear geometry. Synthesis, characterization and the use of organotiniv.
The adsorbed dithiocarbamates are robust under a wide ph range and can resist displacement by other chemisorptive surfactants, providing an attractive method for conjugating sensitive molecules onto metal surfaces. Studies on some dioxouraniumvi complexes with dithiocarbamate ligands. The majority of the complexes studied have simple r 1 and r 2 groups, such as methyl, ethyl and phenyl. Huang, syntheses, crystal structures and antibacterial activities of dithiocarbamate complexes mmebnncs. A highly efficient, mild and simple synthesis of dithiocarbamates is based on the onepot reaction of amines, cs 2, and alkyl halides without using a catalyst under solventfree conditions. With the help of our academic editors, based in institutions around the globe, we are able to focus on serving our authors while. Thus, the protective action of the dithiocarbamate against the toxicity of cisplatin seems to be the formation of its stable platinum dithiocarbamate complexes 7, 10. Synthesis and characterization of homoleptic group 10. Dithiocarbamate fungicides were evaluated several times by the jmpr for toxicology and residues. These complexes have been characterized by elemental analysis, molecular weight measurements, ir and nmr 1 h, c and 119 sn spectroscopy, suggesting that the methyl tin complexes are probably four coordinate, while the phenyl tin ones are probably fivecoordinate with bidentate dithiocarbamate. Abstract monosubstituted dithiocarbamate complexes of light lanthanides of the type rnhcss4lnnbun4nh2o where r dbnd ph, pmeph. Evaluation of the stability constant for the complexes between the metal and dmdc indicate that copper is the only metal that is most likely to inhibit the transformation reactions under conditions.
The cui dithiocarbamates are pale yellow to reddishyellow diamagnetic solids and their melting points decrease with increasing size of the alkyl groups on the ligands. Significant attention has been given to organotiniv dithiocabamate compounds in recent times. Complexes with dithiocarbamate ligands having functional substituted organic groups, such as r 1 and or r 2 equal to ch 2 ch 2 oh, are increasingly being studied, with crystal structures reported for a number of metal complexes including those of alkali metals copper, nickel,, zinc, mercury and antimony. Their discovery was early in the field of sulfur chemistry, with their applications as vulcanisation accelerators and fungicides being explored not long after. The readily available binding sites of the two sulphur atoms within the dithiocarbamate moiety in the complexes confers a wide variety of geometry. The determination of whether dithiocarbamate pesticides share a common mechanism of toxicity from. A series of new dithiocarbamate complexes of niii, pdii and ptii of the form nil 2, pdl 2 and ptl 2 where l nethylnethanoldithiocarbamate have been synthesized and characterized by elemental analysis, ftir, and 1 h and c nmr spectroscopy. Synthesis, characterisation and biological aspects of copper. Synthesis, characterization, and xray crystal structures of znii and hgii complexes and their use as precursors for metal sulfide nanoparticles. The reaction is a highly atomeconomic process for production of salkyl thiocarbamates.
Density functional theory study of goldiiidithiocarbamate complexes with characteristic anticancer potentials. Pdf synthesis, characterization and electrochemical studies. Aspects of its precursors uses to synthesize adducts, nanoparticles, and nanocomposites are reported. It is the analog of a carbamate in which both oxygen atoms are replaced by sulfur atoms when only 1 oxygen is replaced the result is thiocarbamate. Dithiocarbamate article about dithiocarbamate by the. Pdf chemistry and some biological potential of bismuth.
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